| 产品详情 |
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| Antigenic Specificity | TOB1 |
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| Clone | 4B1 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 50 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): Assay Dependent, Western Blot: 0.05-0.1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TOB1 Monoclonal Antibody (4B1). This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 tran |
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| Immunogen | n/a |
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| Other Names | APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1 |
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| Gene, Accession # | Entrez: 10140, 22057; Uniprot: P50616, Q61471 |
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| Catalog # | MA1-24758 |
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| Price | |
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| Order / More Info | TOB1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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