| 产品详情 |
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| Antigenic Specificity | TNPO1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TNPO1 Polyclonal Antibody. SAPK interacting protein 1, a stress-activated protein kinase, is an evolutionarily conserved component of the eukaryotic SAPK pathway belonging to the SIN1 family. There are multiple isoforms with one being a 522-amino acid protein with 2 bipartite nuclear localization signals, a peroxisomal targeting signal, and a PEST motif for rapid protein degradation. SAPK interacting protein 1 forms a complex with inactive and nonphosphorylated MEKK2 and in the process regulates its dimerization and activation. It is also known to maintain CRTC2 complex integrity and regulates Akt phosphorylation and cell signaling. Recent reports suggest that it acts as scaffold molecule in the regulation of signaling by JNK and takes part |
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| Immunogen | n/a |
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| Other Names | SIN-1, MAPKAP1, SIN1, MIP1, MSIN1, mitogen-activated protein kinase associated protein 1, Mitogen-activated protein kinase 2-associated protein 1, SAPK 1, SIN1g, stress-activated protein kinase-interacting 1, stress-activated map kinase interacting protein 1, target of rapamycin complex 2 subunit MAPKAP1, TORC2 subunit MAPKAP1 |
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| Gene, Accession # | Entrez: 238799, 309126, 3842, 478093, 767620; Uniprot: Q3SYU7, Q8BFY9, Q92973 |
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| Catalog # | PA1-41516 |
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| Price | |
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| Order / More Info | TNPO1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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