| 产品详情 |
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| Antigenic Specificity | MARVELD2 |
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| Clone | 54H19L38 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunoprecipitation: 5 µg, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MARVELD2 Antibody (54H19L38), ABfinity™ Rabbit Monoclonal. Tight junctions form an important barrier of paracellular transport in epithelial cells. Sealing of two adjacent cells at bicellular tight junctions, a point where three adjacent cells are in contact with each other. Tricellulin is the first protein identified that specifically concentrates in tricellular tight junctions. This protein has four membrane spanning domains, similarly to claudins. Tricellulin expression is high in epithelium-derived tissues, such as small intestine, kidney and lung. Functional evidence for the role of tricellulin in tight junction formation comes from siRNA studies, where suppression of its expression leads to compromised epithelial barrier and tig |
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| Immunogen | n/a |
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| Other Names | DFNB49, MARVD2, MRVLDC2, Tric, MARVEL (membrane-associating) domain containing 2, MARVEL domain-containing protein 2, tricellulin |
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| Gene, Accession # | Entrez: 153562; Uniprot: Q8N4S9 |
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| Catalog # | 700191 |
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| Price | |
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| Order / More Info | MARVELD2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 23250572, 24229735, 24260326, 27391068, 27492333 |
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