产品详情 |
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Antigenic Specificity | MARVELD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MARVELD1 Polyclonal Antibody. MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity. |
Immunogen | n/a |
Other Names | GB14, MARVD1, MRVLDC1, RP11-548K23.8, bA548K23.8; MARVEL (membrane-associating) domain containing 1; MARVEL domain-containing protein 1; putative MARVEL domain-containing protein 1 |
Gene, Accession # | Entrez: 277010, 309375, 83742; Uniprot: Q7TQJ1, Q9BSK0 |
Catalog # | PA5-20853 |
Price | |
Order / More Info | MARVELD1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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