| 产品详情 |
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| Antigenic Specificity | 14-3-3 delta/zeta |
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| Clone | 1HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | 14-3-3 delta/zeta Antibody (1HCLC), ABfinity™ Rabbit Oligoclonal. At least seven isoforms comprise the highly conserved 14-3-3 family of homo- and heterodimeric proteins that are abundantly expressed in all eukaryotic cells. Although more than seven isoforms of 14-3-3 have been described, some redundancies have appeared upon sequencing. The 14-3-3s are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. By interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle and through interaction with Bad, prevents apoptosis. Other proteins that have been shown to bind to 14-3-3s include members of the protein kinase C family, Cbl, IRS-1, polyoma middle-T antigen |
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| Immunogen | n/a |
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| Other Names | YWHAZ |
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| Gene, Accession # | Entrez: 22631, 25578, 7534; Uniprot: P63101, P63102, P63104 |
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| Catalog # | 711507 |
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| Price | |
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| Order / More Info | 14-3-3 delta/zeta Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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