| 产品详情 |
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| Antigenic Specificity | DFFB |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. This DFFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DFFB. |
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| Immunogen | Human DFFB. |
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| Other Names | DFFB; CAD; DFF2; DFF40; DNA fragmentation factor subunit beta; Caspase-activated deoxyribonuclease; Caspase-activated nuclease; DNA fragmentation factor 40 kDa subunit; dffb- |
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| Gene, Accession # | DFFB, SwissProt: O76075 |
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| Catalog # | abx034537 |
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| Price | |
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| Order / More Info | DFFB Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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