| 产品详情 |
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| Antigenic Specificity | Androgen Receptor |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgA |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq]. Purified His-tagged Androgen Receptor Protein (Fragment) was used to produced this monoclonal antibody. |
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| Immunogen | Human Androgen Receptor Protein. |
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| Other Names | ANDR; Androgen receptor; DHTR; Dihydrotestosterone receptor; NR3C4; AR; AIS; AR8; HUMARA; HYSP1; KD; SBMA; SMAX1; TFM; RP11-383C12.1; Nuclear Receptor Subfamily 3,Group C,Member 4; Testicular Feminization; Kennedy Disease |
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| Gene, Accession # | SwissProt: P10275 |
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| Catalog # | abx025510 |
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| Price | |
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| Order / More Info | Androgen Receptor Antibody from ABBEXA |
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| Product Specific References | n/a |
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