产品详情 |
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Antigenic Specificity | TCCR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 10 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCCR Polyclonal Antibody. Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph |
Immunogen | n/a |
Other Names | UNQ296/PRO336, CRL1, IL27R, TCCR, WSX1, zcytor1; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; T-cell cytokine receptor type 1; class I cytokine receptor; cytokine receptor-like 1; interleukin-27 receptor subunit alpha; type I T-cell cytokine receptor |
Gene, Accession # | Entrez: 9466; Uniprot: Q6UWB1 |
Catalog # | PA5-19984 |
Price | |
Order / More Info | TCCR Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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