| 产品详情 |
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| Antigenic Specificity | TCCR |
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| Clone | 34N4G11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Immunohistochemistry: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCCR Monoclonal Antibody (34N4G11). Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spl |
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| Immunogen | n/a |
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| Other Names | class I cytokine receptor, CRL1IL-27R, Cytokine receptor-like 1, IL27R, IL-27RA, IL-27R-alpha, interleukin 27 receptor, alpha, interleukin-27 receptor subunit alpha, TCCRIL-27 receptor subunit alpha, T-cell cytokine receptor type 1, Type I T-cell cytokine receptor, WSX-1, WSX1IL-27R subunit alpha, zcytor1 |
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| Gene, Accession # | Entrez: 9466; Uniprot: Q6UWB1 |
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| Catalog # | MA5-24795 |
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| Price | |
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| Order / More Info | TCCR Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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