产品名称 PEN2 Antibody from INVITROGEN ANTIBODIES
产品货号 36-7100
产品价格 现货询价,电话:010-67529703
产品规格 50 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPEN2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size50 µg
Concentrationn/a
ApplicationsImmunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent
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DescriptionPEN2 Polyclonal Antibody. Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
Immunogenn/a
Other NamesMDS033, MSTP064, PEN-2, PEN2, gamma-secretase subunit PEN-2, hematopoietic stem/progenitor cells protein MDS033
Gene, Accession #Entrez: 55851, 66340; Uniprot: Q9CQR7, Q9NZ42
Catalog #36-7100
Price
Order / More InfoPEN2 Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 16449647, 21253592, 21280074, 22496554, 22511769, 23843529, 25429133, 26581893, 28383037, 29215028
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