产品名称 PEN2 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-23447
产品价格 现货询价,电话:010-67529703
产品规格 100 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPEN2
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesbovine, canine, equine, human, marsupial, mouse, rat
Isotypen/a
Formatpurified
Size100 ug
Concentrationn/a
ApplicationsWestern Blot: 3-7 µg/mL
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPEN2 Polyclonal Antibody. Presenilin enhancer protein 2 (PEN-2) is a part of a gamma-secreted complex which catalyses the final cleavage of amyloid precursor protein to generate the toxic amyloid beta protein, the major component of plaque in the brains of Alzheimer disease patients. It is an essential subunit of the gamma-secretase complex, and an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). And probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
Immunogenn/a
Other NamesMDS033, MSTP064, PEN-2, PEN2, gamma-secretase subunit PEN-2, hematopoietic stem/progenitor cells protein MDS033
Gene, Accession #Entrez: 100051536, 292788, 476479, 493993, 55851, 66340; Uniprot: Q5G235, Q6QI68, Q9CQR7, Q9NZ42
Catalog #PA5-23447
Price
Order / More InfoPEN2 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料