| 产品详情 |
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| Antigenic Specificity | Factor X |
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| Clone | 5051 |
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| Host Species | Mouse |
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| Reactive Species | bovine, canine, human, ovine, porcine, rabbit |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Inhibition Assays: 5-10 µg/mL, Radioimmune Assays: 5-10 µg/mL, Western Blot: 5-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Factor X Monoclonal Antibody (5051). F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this ge |
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| Immunogen | n/a |
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| Other Names | F10, Coagulation factor 10, Stuart factor |
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| Gene, Accession # | Entrez: 100008647, 101118624, 2159, 280787, 476993, 733662; Uniprot: O19045, P00742, P00743 |
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| Catalog # | MA1-43014 |
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| Price | |
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| Order / More Info | Factor X Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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