| 产品详情 |
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| Antigenic Specificity | MBD3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:100-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MBD3 Polyclonal Antibody. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain. However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. |
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| Immunogen | n/a |
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| Other Names | Methyl-CpG-binding protein MBD3 |
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| Gene, Accession # | Entrez: 53615; Uniprot: O95983 |
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| Catalog # | IHC-00693 |
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| Price | |
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| Order / More Info | MBD3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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