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| Product Name | BAZ2B bromodomain TR-FRET Assay Kit |
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| Description | BAZ2B is a novel bromodomain-containing protein whose biological function, while not yet confirmed, is believed to function similarly to ACF1, the Drosophila BAZ2B ortholog. ACF complexes play roles in establishing regular nucleosome spacing during chromatin assembly and influencing different remodeling outcomes at target loci. Cayman's BAZ2B bromodomain TR-FRET Assay Kit is a homogeneous, TR-FRET assay method amenable to rapid characterization of inhibitors of bromodomain/acetylated peptide interaction in a high throughput format. This screening assay kit is robust, displaying a Z' >0.6. |
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| Size | 1920 well |
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| Concentration | n/a |
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| Applications | High-Throughput Screening, TR-FRET |
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| Other Names | kits assays measures measurements acetylations histones lysines residues epigenetics regulations genes transcriptions acetylated small proteins domains bromodomains regulatory complexes nucleosomes chromatins structures expressions molecules inhibitors BET family tandem Extra Terminals cellular processes inflammatory mitosis viral/host interactions tails bromodomain/histone I-BET JQ-1 humans therapeutics diseases bioinformatic searches BAZ1A BAZ1B BAZ2A C-terminal C-terminus adjacent PHD fingers conserved motifs ACF1 Drosophila orthologoues orthologs catalytic ISWI SNF2h non-catalytic spacing assembly remodeling outcomes targets loci homogeneous Time-Resolved Fluorescence Resonance Energy Transfers peptides HTS high throughput screening formats donor fluorophores amino acids 2064-2168 europium Eu3+ chelates biotinylateds ligands allophycocyanins APC-labeled avidin substrates moiety acceptor |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 600710-1920WELLS |
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| Order / More Info | BAZ2B bromodomain TR-FRET Assay Kit from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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