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Product Name | BAY u9773 |
Description | The biological effects of the cysLTs, including LTC4, LTD4, and LTE4 are transduced mainly by a pair of 7-transmembrane receptors, CysLT1 and CysLT2.{7174.8519,10167} BAY u9773 is a non-selective antagonist of the CysLT receptors, having about the same IC50 (20-80 nM) for the inhibition of LT responses in a variety of tissue preparations containing either/or both receptors.{12765} In contrast, many of the commercially developed CysLT1 receptor antagonists (pranlukast or montelukast) antagonize only CysLT1 receptors. BAY u9773 is thus one of the only available tools for blocking CysLT2 receptors. |
Size | 25 µg |
Concentration | n/a |
Applications | n/a |
Other Names | asthma leukotrienes CysLTs allergy antagonists cysteinyls receptors 7-transmembranes pranlukasts montelukasts CysLT2 CysLT1 CysLT-1 CysLT-2 |
Gene, Accession, CAS # | CAS: 154978-38-8 |
Catalog # | 70770-25 |
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Order / More Info | BAY u9773 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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