| 产品详情 |
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| Product Name | BAY u3405 |
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| Description | The biological effects of PGD2 (Item No. 12010) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and DP2/CRTH2. BAY u3405 (Ramatroban) is an approved human medication for the treatment of allergic rhinitis that has documented activity as an antagonist of the TP receptor.{12335} BAY u3405 is also an antagonist of the DP2 receptor with IC50 values of 100-170 nM.{11248} BAY u3405 is more potent at the DP2 receptor than the TP receptor by 4-5 fold. BAY u3405 is therefore a useful tool for the elucidation of PGD2/DP2 function in eosinophils, basophils, and other cells of the TH2 cell-type. |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Ramatroban |
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| Gene, Accession, CAS # | CAS: 116649-85-5 |
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| Catalog # | 10156-10 |
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| Order / More Info | BAY u3405 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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