产品详情 |
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Product Name | UCN-01 |
Description | A synthetic derivative of staurosporine that inhibits a variety of kinases, including Akt, protein kinase C (IC50 = 30 nM), PDK1 (IC50 = 6 nM) and cyclin-dependent kinases (IC50s = 300-600 nM for Cdk1 and Cdk2); arrests tumor cells in the G1/S phase of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase Chk1 (IC50 = 7 nM), leading to apoptosis |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ?7-hydroxy Staurosporine|NSC 638850 |
Gene, Accession, CAS # | CAS: 112953-11-4 |
Catalog # | 18130-1 |
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Order / More Info | UCN-01 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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