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Product Name | CAY10487 |
Description | The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting ACAT-1 or ACAT-2 activity.{12440,12441} The percent area occupied by the atherosclerotic lesion in rabbits supplemented with 0.05% CAY10487 in the diet was 16.1% compared to 53.5% in control rabbits.{12440} CAY10487 also exhibits antioxidant activity, inhibiting copper-mediated oxidation of LDL by about 75% at a concentration of 2 µM.{12441} |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3,4-Dihydrocinnamic Acid (L-alanine methyl ester) amide |
Gene, Accession, CAS # | CAS: 778624-05-8 |
Catalog # | 10006480-5 |
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Order / More Info | CAY10487 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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