| 产品详情 |
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| Product Name | Thromboxane B1 |
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| Description | DGLA is one of the 20-carbon fatty acids that can be metabolized to PGs and TXs by COX-1/COX-2.{10906} The result of this metabolism in the human platelet yields TXB1. TXB1 is produced in small amounts when DGLA is added to washed suspensions of human platelets, while the major metabolism of this 1-series fatty acid is via 12-LO.{13308} However, when co-incubated with amounts of ethanol often found in intoxicated humans, the metabolism of DGLA shifts to an enhanced production of TXB1.{13308} Urinary TXB1 or its metabolites may thus be a specific biomarker of prior ethanol abuse. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | thromboxanes TXB1 DGLA dihomo-.gamma.-linolenic acids dihomo-g-linolenic metabolites cyclooxygenases COX-1 TXA synthases 20-carbon fatty metabolized prostaglandins COX-2 metabolism human platelets 1-series 12-lipoxygenases 12-LO specific biomarkers ethanol abuses |
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| Gene, Accession, CAS # | CAS: 64626-32-0 |
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| Catalog # | 10006610-1 |
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| Price | |
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| Order / More Info | Thromboxane B1 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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