| 产品详情 |
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| Product Name | GSK2256098 |
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| Description | A FAK inhibitor; selective for FAK over 261 kinases; inhibits FAK autophosphorylation at Y397 in OVCAR8 ovarian, U87MG glioblastoma, and A549 lung cancer cell lines (IC50s = 15, 8.5, and 12 nM, respectively); induces apoptosis, decreases viability (IC50 = 25 µM), and inhibits colony formation in L3.6P1 cells; leads to lower tumor weight and fewer metastases in an orthotopic mouse model of uterine cancer at 75 mg/kg per day |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1416771-10-2 GSK-2256098 Y-397 OVCAR-8 A-549 L36P1 U-87MG U-87-MG |
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| Gene, Accession, CAS # | CAS: 1224887-10-8 |
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| Catalog # | 22955-5 |
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| Price | |
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| Order / More Info | GSK2256098 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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