| 产品详情 |
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| Product Name | GSK1070916 |
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| Description | A potent inhibitor of Aurora B and C (Kis = 0.38 and 1.5 nM, respectively); >250-fold selective for Aurora B and C over Aurora A; inhibits proliferation of A549 lung cancer cells in vitro (EC50 = 7 nM); inhibits proliferation in a panel of 100 tumor cell lines (EC50s = <10 nM); inhibits histone H3 phosphorylation in a COLO 205 mouse xenograft model and induces tumor regression in an HL-60 mouse xenograft model; reduces tumor growth in 10 mouse xenograft models |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GSK-1070916 adenosine triphosphate A-549 colo205 HL60 |
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| Gene, Accession, CAS # | CAS: 942918-07-2 |
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| Catalog # | 22953-1 |
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| Price | |
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| Order / More Info | GSK1070916 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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