产品详情 |
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Antigenic Specificity | JunB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 200 µg |
Concentration | lyophilized |
Applications | ChIP assay: 1-3 µL, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | JunB Polyclonal Antibody. Cellular oncogenes, or proto-oncogenes, play pivotal roles in cellular communication pathways that regulate normal growth, development and differentiation. The cellular oncogene families fos and jun encode nuclear proteins that can function as transcription factors. The fos family of nuclear oncogenes encode cFos, FosB, (fos-related antigen) Fra1, and Fra2. Fos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the `leucine-zipper' motif that allows for dim |
Immunogen | n/a |
Other Names | Oncogene Jun-B |
Gene, Accession # | Entrez: 16477, 3726; Uniprot: P09450, P17275 |
Catalog # | PA1-835 |
Price | |
Order / More Info | JunB Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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