产品详情 |
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Product Name | RG-7112 |
Description | An MDM2 inhibitor (IC50 = 0.018 µM); inhibits proliferation in cancer cell lines expressing wild-type p53 (IC50s = 0.18-2.2 µM) and cell lines expressing mutant p53 (IC50s = 5.7-20.3 µM); prevents and reduces tumor growth in an SJSA-1 mouse xenograft model at 50 and 100 mg/kg per day, respectively; decreases platelet counts in rats at 50 and 100 mg/kg and in cynomolgus monkeys at 10 and 20 mg/kg |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | RO5045337 |
Gene, Accession, CAS # | CAS: 939981-39-2 |
Catalog # | 25673-25 |
Price | |
Order / More Info | RG-7112 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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