| 产品详情 |
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| Product Name | ODM-201 |
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| Description | An androgen receptor antagonist (Ki = 11 nM); inhibits AR transactivation in U2OS osteosarcoma cells expressing human wild-type and mutant ARs (IC50s = 65, 66, 1,500, and 1,782 nM for wild-type, ARF876L, ARW741L, and ART877A, respectively); prevents androgen-induced AR nuclear translocation in AR-overexpressing HS-HEK293 and LNCaP cells; suppresses androgen-induced proliferation of VCaP cells (IC50 = 230 nM); reduces tumor growth in a VCaP castrated mouse xenograft model at 50 mg/kg per day; inhibits tumor growth without increasing serum testosterone levels in a VCaP intact mouse xenograft model , |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BAY 1841788 |
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| Gene, Accession, CAS # | CAS: 1297538-32-9 |
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| Catalog # | 25643-10 |
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| Price | |
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| Order / More Info | ODM-201 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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