| 产品详情 |
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| Product Name | Fasnall (benzenesulfonate) |
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| Description | An inhibitor of FAS (IC50 = 3.71 µM for the human recombinant enzyme); inhibits tritiated acetate incorporation into lipids (IC50 = 5.84 µM), increases ceramide accumulation, and induces the formation of lipid droplets in BT474 HER2+ breast cancer cells; has antiproliferative activity against non-tumorigenic MCF-10A and tumorigenic MCF-7, MDA-MB-468, BT474, and SK-BR-3 breast cancer cells; reduces tumor volume and increases survival in the murine MMTV-Neu model of HER2+ breast cancer; potentiates carboplatin response in vivo, increasing the objective response rate of stable disease from 25% for carboplatin alone to 88% for carboplatin with fasnall, |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BT-474 HER-2+ MCF10A MCF7 MDAMB-468 MDAMB468 SKBR3 anti-proliferative nontumorigenic MMTVNeu |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 19957-1 |
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| Price | |
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| Order / More Info | Fasnall (benzenesulfonate) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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