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Antigenic Specificity | Gata-3 |
Clone | TWAJ |
Host Species | Rat |
Reactive Species | human, mouse, porcine, rhesus monkey |
Isotype | IgG2b, kappa |
Format | eFluor 660 conjugate |
Size | 25 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Gata-3 Monoclonal Antibody (TWAJ), eFluor 660, eBioscience™. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding |
Immunogen | n/a |
Other Names | HDR, MGC2346, MGC5199, MGC5445 |
Gene, Accession # | Entrez: 14462, 2625, 713840, 733631; Uniprot: P23771, P23772 |
Catalog # | 50-9966-41 |
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Order / More Info | Gata-3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19542428, 21677778, 22951729, 23354167, 23922467, 23926350, 24990999, 25672754, 26418311, 26523868, 26883594, 27103660, 28412394, 28506464, 28514688, 28607488, 29588921 |
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