| 产品详情 |
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| Antigenic Specificity | Gata-3 |
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| Clone | TWAJ |
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| Host Species | Rat |
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| Reactive Species | human, mouse, porcine, rhesus monkey |
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| Isotype | IgG2b, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: Assay-Dependent, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Gata-3 Monoclonal Antibody (TWAJ), eBioscience™. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers |
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| Immunogen | n/a |
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| Other Names | HDR, MGC2346, MGC5199, MGC5445 |
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| Gene, Accession # | Entrez: 14462, 2625, 713840, 733631; Uniprot: P23771, P23772 |
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| Catalog # | 14-9966-80 |
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| Price | |
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| Order / More Info | Gata-3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19542428, 21407206, 21498664, 22088562, 22750193, 22951729, 23053511, 23354167, 23720815, 23922467, 24532575, 24705297, 24960164, 25344471, 25575242, 25938477, 26129648, 26141583, 26418311, 26663720, 26663781, 27088444, 27479084, 27588200, 27601626, 27643438, 27883085, 28607488, 29343433, 29588921 |
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