| 产品详情 |
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| Product Name | NSC 668036 |
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| Description | An inhibitor of the Dvl PDZ domain (Kd = 240 µM for mouse Dvl1 PDZ domain); reduces expression of the Wnt target gene, Siamois, in Xenopus embryos and inhibits the ability of injected Wnt3A to induce formation of a secondary axis (180 ng); inhibits proliferation of NIH/3T3 fibroblasts, restrains their migration in a scratch assay, and blocks the accelerating effect of TGF-β on fibroblast migration (>10 µM); reduces the severity of bleomycin-induced pulmonary fibrosis and expression of α-SMA collagen I, TGF-β, and β-catenin in lung in mice (5 mg/kg per day for 14 days) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NSC668036 Wnt-3A TGFβ Dvl-1 αSMA |
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| Gene, Accession, CAS # | CAS: 144678-63-7 |
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| Catalog # | 23499-10 |
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| Price | |
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| Order / More Info | NSC 668036 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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