产品详情 |
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Antigenic Specificity | CREBL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:20-1:50 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CREBL2 Polyclonal Antibody. cAMP response element-binding protein-like-2 was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act a |
Immunogen | n/a |
Other Names | cAMP-responsive element-binding protein-like 2; CREBL2 |
Gene, Accession # | Entrez: 1389; Uniprot: O60519 |
Catalog # | PA5-60489 |
Price | |
Order / More Info | CREBL2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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