产品详情 |
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Antigenic Specificity | DR6 |
Clone | DR-6-04-EC |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DR6 Monoclonal Antibody (DR-6-04-EC), PE. CD358 / DR6 (Death Receptor-6) is a type I transmembrane protein of the TNF receptor superfamily, expressed in most human tissues and able of inducing apoptosis through its cytoplasmic death domain. Unlike TNFR1 and Fas, DR6 induces apoptosis independently of FADD adaptor. In immune system, DR6 serves as an important regulator for CD4+ T cell proliferation and Th differentiation, and provides also a regulatory mechanism for B cell activation and humoral immune responses. |
Immunogen | n/a |
Other Names | Death receptor-6 |
Gene, Accession # | Entrez: 27242; Uniprot: O75509 |
Catalog # | MA1-19720 |
Price | |
Order / More Info | DR6 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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