| 产品详情 |
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| Antigenic Specificity | DR4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay-dependent, Immunohistochemistry (Paraffin): Assay dependent, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR4 Polyclonal Antibody. Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified and termed TRAIL (2,3), which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1)(4). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells. |
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| Immunogen | n/a |
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| Other Names | APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1 |
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| Gene, Accession # | Entrez: 8797; Uniprot: O00220 |
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| Catalog # | PA1-30795 |
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| Price | |
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| Order / More Info | DR4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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