| 产品详情 |
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| Antigenic Specificity | DR4 |
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| Clone | DR-4-02 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR4 Monoclonal Antibody (DR-4-02), FITC. Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand). TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-βB activation in many tissues |
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| Immunogen | n/a |
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| Other Names | APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1 |
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| Gene, Accession # | Entrez: 8797; Uniprot: O00220 |
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| Catalog # | A15746 |
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| Price | |
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| Order / More Info | DR4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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