| 产品详情 |
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| Antigenic Specificity | DR4 |
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| Clone | DR-4-02 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 3-5 µg/mL, Functional Assay: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR4 Monoclonal Antibody (DR-4-02). TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor). |
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| Immunogen | n/a |
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| Other Names | APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1 |
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| Gene, Accession # | Entrez: 8797; Uniprot: O00220 |
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| Catalog # | MA1-19025 |
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| Price | |
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| Order / More Info | DR4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21037225 |
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