| 产品详情 |
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| Antigenic Specificity | DR4 |
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| Clone | 32A242 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR4 Monoclonal Antibody (32A242). Cells undergo programmed cell death (Apoptosis) in response to various stimuli. Apoptosis is essential for morphogenesis, tissue homeostasis, and host defense (5). Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4) (4). The ligand for this novel death receptor has been identified and termed TRAIL (2,3), which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1) (1). DR4 is expressed in most human tissues including spleen, peripheral blood leukocytes, small intestine and thy |
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| Immunogen | n/a |
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| Other Names | APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1 |
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| Gene, Accession # | Entrez: 8797; Uniprot: O00220 |
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| Catalog # | MA1-41049 |
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| Price | |
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| Order / More Info | DR4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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