| 产品详情 |
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| Antigenic Specificity | DR3 |
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| Clone | 59204 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Flow Cytometry: 2.5 µg/1x10^6 cells, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR3 Monoclonal Antibody (59204). The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing o |
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| Immunogen | n/a |
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| Other Names | APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR, apoptosis inducing receptor, apoptosis-inducing receptor AIR, apoptosis-mediating receptor DR3, apoptosis-mediating receptor TRAMP, death domain receptor 3 soluble form, death receptor beta, lymphocyte-associated receptor of death, protein WSL-1, tumor necrosis f |
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| Gene, Accession # | Entrez: 85030, 8718; Uniprot: Q93038 |
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| Catalog # | MA5-23838 |
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| Price | |
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| Order / More Info | DR3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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