产品详情 |
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Antigenic Specificity | DR3 |
Clone | 11H6L9 |
Host Species | Recombinant Rabbit |
Reactive Species | human, mouse |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DR3 Antibody (11H6L9), ABfinity™ Rabbit Monoclonal. DR3/TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of DR3/TNFRSF25 in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative sp |
Immunogen | n/a |
Other Names | Tumor necrosis factor receptor superfamily member 25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1 |
Gene, Accession # | Entrez: 85030, 8718; Uniprot: Q93038 |
Catalog # | 702277 |
Price | |
Order / More Info | DR3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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