| 产品详情 |
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| Antigenic Specificity | DR1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:500-1:1000, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR1 Polyclonal Antibody. This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. |
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| Immunogen | n/a |
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| Other Names | Down-regulator of transcription 1, TBP-binding (negative cofactor 2), NC2, NC2-BETA |
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| Gene, Accession # | Entrez: 1810; Uniprot: Q01658 |
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| Catalog # | PA5-63106 |
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| Price | |
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| Order / More Info | DR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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