| 产品详情 |
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| Product Name | Bufexamac |
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| Description | An NSAID and a class IIb HDAC inhibitor; inhibits IFN-α production in PBMCs (EC50 = 8.9 µM); induces hyperacetylation of tubulin (IC50 = 2.9 µM); inhibits LTA4 hydrolase and aminopeptidase activity (IC50s = 15.86 and 11.59 µM, respectively); inhibits 5-LO (IC50 = 27 µM); inhibits the production of LTB4 in neutrophils (IC50 = 12.91 µM) and reduces fMLP-induced neutrophil migration at 50 and 100 µM; reduces neutrophil levels, as well as TNF-α and IL-1β protein levels, in BALF in a mouse model of LPS-induced acute lung injury at 100 mg/kg |
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| Size | 1 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Anderm CP 1044J3 Droxarol droxaryl Feximac Flogocid Malipuran Mofenar Norfemac Parfenac Parfenal Trolab HDAC-6 -10 IFNα H3-K5 5LO IL1β |
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| Gene, Accession, CAS # | CAS: 2438-72-4 |
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| Catalog # | 26068-1 |
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| Price | |
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| Order / More Info | Bufexamac from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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