| 产品详情 |
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| Product Name | LAS191859 |
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| Description | A CRTH2/DP2 antagonist (IC50s = 9.58, 14, 15.5, and 7.6 nM for recombinant human, rat, mouse, and guinea pig CRTH2/DP2 receptors, respectively); selective for CRTH2/DP2 over a panel of 65 enzymes, ion channels, and transporters with 2-induced shape change of eosinophils (IC50s = 2 and 8.2 nM in isolated eosinophils and whole blood, respectively) and eosinophil chemotaxis (IC50 = 1.3 nM); reduces PGD2-induced systemic eosinophilia in guinea pigs (ID50 = 131 µg/kg) |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LAS-191859 PGD-2 CRTH-2 DP-2 Chemoattractant-receptor Homologous Molecule Expressed on Th2 Cells |
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| Gene, Accession, CAS # | CAS: 1420071-13-1 |
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| Catalog # | 20238-1 |
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| Price | |
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| Order / More Info | LAS191859 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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