| 产品详情 |
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| Product Name | Riociguat |
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| Description | A stimulator of sGC; stimulates recombinant sGC in a concentration-dependent manner in vitro by up to 73-fold at 100 µM or by up to 112-fold when used in combination with DEA NONOate; has no effect on phosphodiesterases PDE1-9 and PDE11 at ≤3 µM; reduces pulmonary and systemic arterial pressure at 1 and 10 mg/kg in a rabbit model of acute PAH induced by U-46619; inhibits increases in right ventricular systolic pressure, right heart hypertrophy, and pulmonary artery muscularization in hypoxia-induced mouse and monocrotaline-injected rat models of chronic PAH at 10 mg/kg |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BAY 63-2521 |
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| Gene, Accession, CAS # | CAS: 625115-55-1 |
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| Catalog # | 9000554-10 |
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| Price | |
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| Order / More Info | Riociguat from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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