| 产品详情 |
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| Product Name | (−)-FINO2 |
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| Description | A ferroptosis inducer; an indirect GPX4 inhibitor and iron oxidizer; decreases GPX4 activity and protein levels in vitro; oxidizes iron in vitro; induces lipid peroxidation of a large subset of the lipidome in HT-1080 cells at 10 µM; induces ferroptosis in an arachidonic acid lipoxygenase-independent manner; inhibits growth of and induces lethality in the NCI-60 panel of cancer cell lines (mean GI50 = 5.8 µM; mean LC50 = 46 µM); selective for oncogenically transformed BJ-ELR cells over noncancerous BJ-hTERT cells at 15 and 20 µM; induces oxidative stress, including lipid peroxidation, in RS4;11 B-lymphoblastic leukemia cells at 6 µM |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 869298-31-7 |
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| Catalog # | 25096-10 |
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| Price | |
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| Order / More Info | (−)-FINO2 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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