| 产品详情 |
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| Product Name | TNP-ATP (triethylammonium salt) |
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| Description | An antagonist of P2X receptors and a fluorescent probe; an antagonist at the purinergic receptor subtypes P2X1, P2X3, and P2X2/3 (IC50s = 6, 0.9, and 7 nM, respectively); selective over P2X2, P2X4, and P2X7 receptors (IC50s = 2,000, 15,200, and >30,000 nM, respectively); inhibits calcium flux in 1321N1 cells expressing P2X3 and P2X2/3 receptors (IC50s = 10 and 62 nM, respectively); reduces acetic-acid induced writhing in a mouse model of visceral pain (ED50 = 6.35 µmol/kg); fluorescent probe for ATP-binding enzyme activity with ex/em = 403 and 547 nm, respectively, with a four-fold increase in intensity and an emission shift to 538 nm upon binding to the ATP-binding enzyme IDE , |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | Fluorescence, TR-FRET |
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| Other Names | 1417343-82-8 61368-63-6 TNPATP P-2X P-2-X P-3X P-3-X P-2/3X P-2/3-X P-4X P-4-X P-7X P-7-X 1321-N1 1321-N-1 P2X-1 3 2/3 2 4 7 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 20902-5 |
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| Price | |
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| Order / More Info | TNP-ATP (triethylammonium salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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