| 产品详情 |
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| Product Name | Gabaculine (hydrochloride) |
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| Description | An irreversible inhibitor of GABA-T (Ki = 2.9 µM); irreversibly inhibits D-amino acid transaminase, L-alanine transaminase, and L-aspartate transaminase (Kis = 0.1, 1, and 55 mM, respectively); irreversibly inhibits ornithine aminotransferase in vitro and in mouse brain and liver homogenates; increases latency to convulsion in the 3-mercaptopropionic acid-induced and minimal electroshock-induced seizure models (ED50s = 135 and 200 mg/kg, respectively); inhibits 3-mercaptopropionic acid-induced increases in GAD and GABA-T activity in mice (ED50s = 135 mg/kg); LD50 = 62 mg/kg; elevates concentrations of GABA in mouse brain by over 500% and reduces GABA-T activity to below detection limits (135 mg/kg, i.p.) |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 59556-18-2 123937-87-1 GABAT 3-MA 3MA |
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| Gene, Accession, CAS # | CAS: 59556-17-1 |
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| Catalog # | 24209-5 |
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| Price | |
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| Order / More Info | Gabaculine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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