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| Product Name | D-myo-Inositol-2,4,5-triphosphate (sodium salt) |
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| Description | The inositol phosphates (InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals.{8344,8672} The most studied InsP, Ins(1,4,5)P3, more commonly referred to as IP3, is a second messenger produced in cells by PLC-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate.{2429,5714} Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.{5714,4096} Ins(2,4,5)P3 is a metabolically stable analog of Ins(1,4,5)P3 that is commonly used to study Ca2+ signaling pathways. Ins(2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins(1,4,5)P3.{13732} |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,4,5-IP3 (sodium salt)|Ins(2,4,5)P3 (sodium salt) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 10007779-100 |
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| Order / More Info | D-myo-Inositol-2,4,5-triphosphate (sodium salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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