| 产品详情 |
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| Antigenic Specificity | CTTN |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq). |
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| Immunogen | Purified recombinant fragment of human CTTN expressed in E. Coli. |
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| Other Names | CTTN; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1; FLJ34459 |
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| Gene, Accession # | Gene ID: 2017, SwissProt: Q14247 |
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| Catalog # | abx012196 |
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| Price | |
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| Order / More Info | CTTN Antibody from ABBEXA |
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| Product Specific References | n/a |
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