产品详情 |
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Product Name | Isotretinoin |
Description | A retinoid; increases the doubling time and transcription of RARβ mRNA in various human oral squamous cell carcinoma cells at 1 µM; inhibits proliferation of primary human sebocytes (IC50 = 10 µM); decreases triglyceride, stearyl ester, and free fatty acid synthesis and modulates keratin expression in primary human sebocytes at 0.1 µM; reduces chronic rejection damage and decreases mRNA expression of IFN-γ and IL-10 in allografts in chronic Fisher344?Lewis transplant mice at 2 mg/kg per day; slows rod and cone recovery and prevents light-induced photoreceptor damage in an albino rat model of photoreceptor degeneration at 40 mg/kg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 13(Z)-Retinoic Acid|13-cis-Vitamin A Acid|AGN 190013 |
Gene, Accession, CAS # | CAS: 4759-48-2 |
Catalog # | 21648-50 |
Price | |
Order / More Info | Isotretinoin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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