产品详情 |
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Antigenic Specificity | alpha Actinin 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | alpha Actinin 4 Polyclonal Antibody. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involve |
Immunogen | n/a |
Other Names | ACTININ-4, FSGS, FSGS1, F-actin cross-linking protein, actinin alpha4 isoform, alpha-actinin-4, focal segmental glomerulosclerosis 1, non-muscle alpha-actinin 4 |
Gene, Accession # | Entrez: 60595, 63836, 81; Uniprot: O43707, P57780, Q9QXQ0 |
Catalog # | PA5-27475 |
Price | |
Order / More Info | alpha Actinin 4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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