产品详情 |
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Antigenic Specificity | alpha Actinin 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | alpha Actinin 3 Polyclonal Antibody. The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and alpha-actinins. There are four tissue-specific alpha-actinins, namely alpha-actinin-1, alpha-actinin-2, alpha-actinin-3 and alpha-actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each alpha-actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding alpha-a |
Immunogen | n/a |
Other Names | Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, ACTN3, alpha-Actinin3, Actinin alpha3, Actinin alpha3, alphaActinin-3, Actinin-alpha3, alpha-actinin-3 |
Gene, Accession # | Entrez: 11474, 171009, 89; Uniprot: O88990, Q08043 |
Catalog # | PA5-36233 |
Price | |
Order / More Info | alpha Actinin 3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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