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| Product Name | Deferasirox |
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| Description | An orally bioavailable iron chelator with anticancer activity; selective for (Fe(III) over Cu(II), Zn(II), Mg(II), and Ca(II) but does bind to Al(III); decreases iron levels in iron-loaded rat heart cells in vitro by 45.8 and 55.6% compared to control levels at 160 and 320 µM; decreases radiolabeled liver iron levels from 41 to 21.7% and blood iron levels from 8.2 to 3.4% in hypertransfused rats at 200 mg/kg; inhibits proliferation of SAS human oral squamous carcinoma cells (EC50 = 21 µM); act synergistically with gemcitabine in vitro to inhibit proliferation and in vivo to reduce tumor growth at 200 mg/kg in a BxPC-3 mouse xenograft model |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ICL670A |
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| Gene, Accession, CAS # | CAS: 201530-41-8 |
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| Catalog # | 16753-5 |
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| Price | |
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| Order / More Info | Deferasirox from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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