产品详情 |
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Antigenic Specificity | CD8a |
Clone | G28 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG2a, κ |
Format | phycoerythrin (PE) conjugate |
Size | 200 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-rat CD8a. CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck). |
Immunogen | CD8+ Wistar rat splenic T cell hybridomas |
Other Names | CD8a, T8, Lyt2, Ly-2, Leu-8 |
Gene, Accession # | Gene ID: 24930 |
Catalog # | 200608 |
Price | |
Order / More Info | CD8a Antibody from BIOLEGEND |
Product Specific References | PubMed: 24829408 |
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